EC 5.1.3.2 is an enzyme commission (EC) number that represents the enzyme isocitrate dehydrogenase (IDH), which plays a crucial role in the citric acid cycle (also known as the Krebs cycle or TCA cycle). This enzyme catalyzes the oxidative decarboxylation of isocitrate to produce alpha-ketoglutarate, CO2, and NADPH (in the case of IDH1 and IDH2) or NADH (in the case of IDH3). The NADPH generated by IDH1 and IDH2 is essential for the biosynthesis of fatty acids, cholesterol, and other cellular components, while NADH produced by IDH3 is used in the electron transport chain to generate ATP. Mutations in the genes encoding IDH enzymes have been implicated in various cancers and neurological disorders, making them a target for therapeutic intervention.
The CAS Registry Mumber 9032-89-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,3 and 2 respectively; the second part has 2 digits, 8 and 9 respectively. Calculate Digit Verification of CAS Registry Number 9032-89: (6*9)+(5*0)+(4*3)+(3*2)+(2*8)+(1*9)=97 97 % 10 = 7 So 9032-89-7 is a valid CAS Registry Number.