90323-30-1

Basic information

• Product Name: 1-Methyl-6-nitro-1,2,3,4-tetrahydroquinoxaline-2,3-dione
• Synonyms: 1-Methyl-6-nitro-1,2,3,4-tetrahydroquinoxaline-2,3-dione
• CAS NO: 90323-30-1
• Molecular Formula: C9H7N3O4
• Molecular Weight: 221
• Mol File: 90323-30-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Methyl-6-nitro-1,2,3,4-tetrahydroquinoxaline-2,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-6-nitro-1,2,3,4-tetrahydroquinoxaline-2,3-dione(90323-30-1)
• EPA Substance Registry System: 1-Methyl-6-nitro-1,2,3,4-tetrahydroquinoxaline-2,3-dione(90323-30-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 90323-30-1(Hazardous Substances Data)

Usage

General Description

1-Methyl-6-nitro-1,2,3,4-tetrahydroquinoxaline-2,3-dione is a chemical compound with the molecular formula C9H9N3O4. It is a nitro-substituted quinoxaline derivative and it has a yellow crystalline appearance. 1-Methyl-6-nitro-1,2,3,4-tetrahydroquinoxaline-2,3-dione is known to have biological activity, specifically as an inhibitor of certain enzymes such as nitric oxide synthase. It has also been studied for its potential as a pharmaceutical agent, particularly in the treatment of neurodegenerative diseases and other conditions involving the central nervous system. Additionally, it has shown potential as a precursor for the synthesis of other organic compounds with various applications.

Upstream product

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Relevant articles and documents

Green synthesis method of N-substituted-1,4-dihydro-2,3-quinoxalinedione compound

The invention discloses a green synthesis method of an N-substituted-1,4-dihydro-2,3-quinoxalinedione compound. The green synthesis method comprises the following steps: reacting ammonium persulfate with an N-substituted quinoxaline-2(1H)-one derivative in an aqueous solution of DL-alpha-tocopherol methoxy polyethylene glycol succinic acid water to generate the N-substituted-1,4-dihydro-2,3-quinoxalinedione compound; and after the reaction is finished, extracting a reaction product by using ethyl acetate, and performing vacuum drying to obtain the high-purity target product. The aqueous solution of the DL-alpha-tocopherol methoxy polyethylene glycol succinic acid can be recycled at least five times or more. The method is good in product selectivity, high in yield, simple in separation process, low in raw material cost, friendly to environment and beneficial for industrial production and application.

Synthesis and in vitro and in vivo biological evaluation of substituted nitroquinoxalin-2-ones and 2,3-diones as novel trichomonacidal agents

Two series of ten novel 7-nitroquinoxalin-2-ones and ten 6-nitroquinoxaline-2,3-diones with diverse substituents at positions 1 and 4 were synthesized and evaluated against the sexually transmitted parasite Trichomonas vaginalis. Furthermore, diverse mole