Hemoglobin C-Harlem is a rare genetic variant of the hemoglobin molecule, specifically a point mutation in the beta-globin gene, which results in the substitution of the amino acid lysine for glutamic acid at the sixth position. This alteration affects the structure and function of the hemoglobin molecule, leading to a mild form of hemoglobinopathy. Individuals with hemoglobin C-Harlem typically have a higher concentration of hemoglobin C, which can cause red blood cells to become more rigid and less flexible. This can lead to a reduced ability to transport oxygen and, in some cases, may result in symptoms similar to those of sickle cell anemia, such as pain crises, anemia, and increased risk of infections. However, the severity of these symptoms is generally less pronounced compared to other hemoglobinopathies, and many individuals with hemoglobin C-Harlem can lead relatively normal lives with proper management and care.
The CAS Registry Mumber 9034-57-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,3 and 4 respectively; the second part has 2 digits, 5 and 7 respectively. Calculate Digit Verification of CAS Registry Number 9034-57: (6*9)+(5*0)+(4*3)+(3*4)+(2*5)+(1*7)=95 95 % 10 = 5 So 9034-57-5 is a valid CAS Registry Number.