Hemoglobin G San Jose is a rare variant of the hemoglobin molecule, specifically a hemoglobinopathy, which is a genetic disorder affecting the structure or function of hemoglobin. This particular variant is caused by a mutation in the HBA2 gene, leading to the substitution of the amino acid glutamic acid with lysine at the 121st position in the beta-globin chain. First identified in a family from San Jose, Costa Rica, hemoglobin G San Jose is associated with mild clinical symptoms, such as mild anemia, and is generally considered to be benign. It is important to note that while this variant may not cause severe health issues, individuals with hemoglobinopathies should consult with medical professionals for proper diagnosis and management.
The CAS Registry Mumber 9034-75-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,3 and 4 respectively; the second part has 2 digits, 7 and 5 respectively. Calculate Digit Verification of CAS Registry Number 9034-75: (6*9)+(5*0)+(4*3)+(3*4)+(2*7)+(1*5)=97 97 % 10 = 7 So 9034-75-7 is a valid CAS Registry Number.