Cas 90340-70-8,Benzoic acid, 2-[(1E)-2-(2-naphthalenyl)ethenyl]-, ethyl ester

90340-70-8

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Basic information

Product Name: Benzoic acid, 2-[(1E)-2-(2-naphthalenyl)ethenyl]-, ethyl ester
Synonyms:
CAS NO:90340-70-8
Molecular Formula: C21H18O2
Molecular Weight: 302.373
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Benzoic acid, 2-[(1E)-2-(2-naphthalenyl)ethenyl]-, ethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-[(1E)-2-(2-naphthalenyl)ethenyl]-, ethyl ester(90340-70-8)
EPA Substance Registry System: Benzoic acid, 2-[(1E)-2-(2-naphthalenyl)ethenyl]-, ethyl ester(90340-70-8)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 90340-70-8(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 90340-70-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,3,4 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 90340-70:
(7*9)+(6*0)+(5*3)+(4*4)+(3*0)+(2*7)+(1*0)=108
108 % 10 = 8
So 90340-70-8 is a valid CAS Registry Number.

90340-70-8Upstream product

90340-70-8Downstream Products

90340-70-8Relevant academic research and scientific papers

Benzoylalanine-derived ketoamides carrying vinylbenzyl amino residues: Discovery of potent water-soluble calpain inhibitors with oral bioavailability

Lubisch, Wilfried,Beckenbach, Edith,Bopp, Sabina,Hofmann, Hans-Peter,Kartal, Arzu,K?stel, Claudia,Lindner, Tanja,Metz-Garrecht, Marion,Reeb, Jutta,Regner, Ferdinand,Vierling, Michael,M?ller, Achim

, p. 2404 - 2412 (2007/10/03)

Novel benzoylalanine-derived ketoamides were prepared and evaluated for calpain I inhibition. Derivatives carrying vinylbenzyl amino residues in the P2 - P3 region inhibited calpain in nanomolar concentrations and thus represent a novel class of nonpeptidic calpain inhibitors. Selected examples exhibited an improved pharmacokinetic profile including improved watersolubility and metabolic stability. In particular, these calpain inhibitors showed oral bioavailability in rats as demonstrated by N-(1-benzyl-2-carbamoyl-2-oxoethyl)-2- [E-2-(4-diethylaminomethylphenyl)ethen-1-yl]benzamide (5d). The closely related derivative N-(1-carbamoyl-1-oxohex-1-yl)-2-[E-2- (4-dimethylaminomethylphenyl)-ethen-1-yl]benzamide (5b) was evaluated for neuroprotective efficacy after experimental traumatic brain injury in a fluid percussion model in rats. When administered after injury, 5b reduced the number of damaged neurons by 41%, and this result would be in line with the suggested neuroprotective efficacy of calpain inhibition.

Benzamidoaldehydes and their use as cysteine protease inhibitors

-

, (2008/06/13)

Compounds of the formula where R1, R2, R3, X and n are as defined in the description, are inhibitors of cysteine protease.

The Photochemistry of Alkyl 2-(Naphthalenyl)ethenylbenzoates:Photodehydrocyclization and Photodimerization Products and Their Structural Elucidation by 1H and 13C N.M.R.

Jones, Alan J.,Teitei, Tsutomu

, p. 561 - 576 (2007/10/02)

Irradiation of alkyl 2-benzoates in benzene gave the photodehydrocyclization product, the chrysenecarboxylates (3) as well as two of the photodimerization products, the cyclobutanes (6) and (7).Similarly, irradiation of alkyl 2

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