Hemoglobin O Indonesia is a rare hemoglobin variant found predominantly in the Indonesian population. It is caused by a genetic mutation in the HBB gene, which encodes the beta-globin chain of hemoglobin. This mutation results in a structural change in the hemoglobin molecule, leading to altered oxygen-binding properties and potentially causing mild hemolytic anemia. Hemoglobin O Indonesia is inherited in an autosomal recessive manner, meaning that an individual must inherit two copies of the mutated gene (one from each parent) to express the condition. While it is relatively benign in most cases, it can lead to complications in individuals with other hemoglobinopathies, such as sickle cell anemia or beta-thalassemia.
The CAS Registry Mumber 9035-18-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,3 and 5 respectively; the second part has 2 digits, 1 and 8 respectively. Calculate Digit Verification of CAS Registry Number 9035-18: (6*9)+(5*0)+(4*3)+(3*5)+(2*1)+(1*8)=91 91 % 10 = 1 So 9035-18-1 is a valid CAS Registry Number.