Hemoglobin Zurich is a rare variant of the hemoglobin molecule, specifically a hemoglobinopathy, which is a genetic disorder affecting the structure or function of hemoglobin. This particular variant is caused by a point mutation in the beta-globin gene, leading to the substitution of the amino acid glutamic acid with lysine at the 121st position of the beta chain. As a result, hemoglobin Zurich exhibits altered oxygen-binding properties, which can affect the oxygen-carrying capacity of red blood cells. Individuals with this variant may experience mild to moderate anemia, and in some cases, it can be asymptomatic. Hemoglobin Zurich is inherited in an autosomal recessive manner, meaning that an individual must inherit two copies of the mutated gene, one from each parent, to express the condition.
The CAS Registry Mumber 9035-33-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,3 and 5 respectively; the second part has 2 digits, 3 and 3 respectively. Calculate Digit Verification of CAS Registry Number 9035-33: (6*9)+(5*0)+(4*3)+(3*5)+(2*3)+(1*3)=90 90 % 10 = 0 So 9035-33-0 is a valid CAS Registry Number.