903529-01-1Relevant academic research and scientific papers
An efficient conversion of the carboxylic group of N-Fmoc α-amino acids/peptide acids into N-formamides employing isocyanates as key intermediates
Sudarshan,Narendra,Hemantha,Sureshbabu, Vommina V.
, p. 9804 - 9807 (2008/03/27)
(Chemical Equation Presented) Reaction of 96% formic acid with isocyanates derived from N-Fmoc α-amino acids/peptide acids catalyzed by DMAP has yielded a new class of stable formamides as crystalline solids which have been characterized by IR, 1/su
Preparation, isolation, and characterization of Nα-Fmoc- peptide isocyanates: Solution synthesis of oligo-α-peptidyl ureas
Sureshbabu, Vommina V.,Patil, Basanagoud S.,Venkataramanarao, Rao
, p. 7697 - 7705 (2007/10/03)
(Chemical Equation Presented) The Nα-Fmoc-peptide isocyanates 3a-q, 4a-c, and 5a-c were prepared by the Curtius rearrangement of Nα-Fmoc-peptide acid azides in toluene under thermal, microwave, and ultrasonic conditions. All the Nsu
Nα-Fmoc-peptide azides: Synthesis, isolation, characterization and utility in the extension of peptide chains
Suresh Babu, Vommina V.,Vasanthakumar, Ganga-Ramu,Patil, Basanagoud S.
, p. 1853 - 1858 (2007/10/03)
Syntheses of Nα-Fmoc-peptide azides employing acid chloride as well as mixed anhydride methods have been carried out. The resulting Fmoc-peptide azides prepared have been isolated as solids in good yield (75-92 %) and are found to be analytical
