903563-75-7

Upstream product

• 100-46-9 benzylamine 
• 903563-71-3 2-(benzylamino-methyl)-3-(2-chloro-phenyl)-3-hydroxy-propionitrile 
• 32459-62-4 4-ethoxyphenyl isocyanate 

Relevant academic research and scientific papers

Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives

The synthesis of several 1-(2-cyano-3-aryl-allyl)-3-aryl-urea(thiourea) constructed from the reaction between allylamines generated from Baylis-Hillman acetates and substituted isocyanates and isothiocyanates has been described. Further, their cyclization in the presence of a base led to the formation of 5-arylmethyl-4-imino-3-aryl-3,4-dihydro-1H-pyrimidin-2-ones. All compounds were tested for their antibacterial activity. Few of the compounds showed superior activity or were equipotent to the standard antibacterial agents.