90359-75-4Relevant academic research and scientific papers
Directed Metalation of N,N-Diethylbenzamides. Silylated Benzamides for the Synthesis of Naturally Occurring pero-Methylanthraquinones and peri-Methyl Polycyclic Aromatic Hydrocarbons
Mills, Robert J.,Snieckus, Victor
, p. 4386 - 4390 (2007/10/02)
Efficient methodologies based on directed ortho metalation, fluoride-induced carbodesilylation, and metal-halogen exchange processes (Scheme I) are reported for the synthesis of peri-methyl-substituted anthraquinone natural products 5 and polycyclic aroma
SILICON IN BENZAMIDE DIRECTED ORTHO METALATION REACTIONS SYNTHESIS OF PERI-METHYL SUBSTITUTED PAHs AND NATURAL ANTHRAQUINONES
Mills, R.J.,Snieckus, V.
, p. 479 - 482 (2007/10/02)
The α,α-bis(trimethylsilyl)-o-toluamides 4 and 9, systems protected from benzylic deprotonation, are available starting materials for the short syntheses of peri-methyl substituted benz(a)anthraquinones 6a and 6b and desoxyerythrolaccin trimethyl ether 12 respectively.
