90365-63-2

Basic information

• Product Name: 4-Octanol, (S)-
• Synonyms: (S)-octan-4-ol;4-Octanol, (S)-;Octanol-4
• CAS NO: 90365-63-2
• Molecular Formula: C8H18O
• Molecular Weight: 130.23
• Mol File: 90365-63-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 179.2±8.0 °C(Predicted)
• Density: 0.821±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-Octanol, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Octanol, (S)-(90365-63-2)
• EPA Substance Registry System: 4-Octanol, (S)-(90365-63-2)

Safety Data

• Hazardous Substances Data: 90365-63-2(Hazardous Substances Data)

Upstream product

• 589-62-8 octan-4-ol 

Downstream Products

• 1117-32-4 (-)(R)-4-iodo-octane 

Relevant articles and documents

Biocatalytic Racemization Employing TeSADH: Substrate Scope and Organic Solvent Compatibility for Dynamic Kinetic Resolution

Racemization in combination with a kinetic resolution is the base for a dynamic kinetic resolution (DKR). Biocatalytic racemization was successfully performed for a broad scope of sec-alcohols by employing a single alcohol dehydrogenase (ADH) variant from Thermoanaerobacter pseudoethanolicus (formerly T. ethanolicus; TeSADH W110A I86A C295A). The catalyst employed as a lyophilized whole cell preparation or cell free extract, which tolerated various non-water miscible organic solvents under micro-aqueous or two-phase conditions, whereby cyclohexane and n-hexane suited best. Various concepts for combining the enzymatic racemization with an enzymatic kinetic resolution to achieve overall a bis-enzymatic DKR were evaluated. A proof of concept showed a successful DKR with racemization in aqueous phase combined with acylation in the organic phase.