903674-76-0Relevant academic research and scientific papers
Facile cuI-catalyzed arylation of azoles and amides using simple enaminones as efficient ligands
Cheng, Cungui,Sun, Gonglei,Wan, Jieping,Sun, Cuirong
experimental part, p. 2663 - 2668 (2010/01/16)
(E)-3-(Dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one was found to be an excellent ligand for copper-catalyzed N-arylation of azoles and amides with aryl halides under mild conditions. The reaction took place at 82 C in MeCN with broad functional-group compatibility. A combination of the ligand and CuI proved to be an efficient catalytic system to promote the coupling reactions of aryl halides with azoles and amides.
