Exonuclease III, a member of the exonuclease family, is an enzyme that plays a pivotal role in DNA repair and recombination within cells. It is characterized by its 3' to 5' exonuclease activity, which enables it to cleave phosphodiester bonds and remove mono-, di-, or trinucleotides from the 3' end of double-stranded DNA. This function is crucial for the repair of DNA damage induced by various factors, including radiation, oxidative stress, and chemicals, thereby ensuring the maintenance of genomic stability and integrity. Exonuclease III also serves as a valuable tool in biotechnology and molecular biology research for DNA manipulation and sequencing.
9037-44-9
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Basic information
- Product Name: EXONUCLEASE III
- Synonyms: EXONUCLEASE III LE;Nuclease, exodeoxyribo-, III;EC 3.1.11.2;EXONUCLEASE III
- CAS NO:9037-44-9
- Molecular Formula:
- Molecular Weight: 0
- EINECS: 232-912-1
- Product Categories: 3.1.x.x Acting on esters;3.x.x.x Hydrolases;Enzyme Class Index
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /buffered aqueous glycerol solution
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: EXONUCLEASE III(CAS DataBase Reference)
- NIST Chemistry Reference: EXONUCLEASE III(9037-44-9)
- EPA Substance Registry System: EXONUCLEASE III(9037-44-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: 36
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 9037-44-9(Hazardous Substances Data)
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9037-44-9 Usage
Uses
Used in Biotechnology and Molecular Biology Research:Exonuclease III is utilized as a tool for DNA manipulation and sequencing, facilitating the study of genetic information and the development of novel therapeutic strategies.
Used in DNA Repair and Recombination:
This enzyme is employed in the repair of DNA damage caused by radiation, oxidative stress, and certain chemicals, contributing to the preservation of genomic stability and integrity.
Check Digit Verification of cas no
The CAS Registry Mumber 9037-44-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,3 and 7 respectively; the second part has 2 digits, 4 and 4 respectively.Calculate Digit Verification of CAS Registry Number 9037-44:
(6*9)+(5*0)+(4*3)+(3*7)+(2*4)+(1*4)=99
99 % 10 = 9
So 9037-44-9 is a valid CAS Registry Number.
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EXONUCLEASE III
