9037-44-9

Basic information

• Product Name: EXONUCLEASE III
• Synonyms: EXONUCLEASE III LE;Nuclease, exodeoxyribo-, III;EC 3.1.11.2;EXONUCLEASE III
• CAS NO: 9037-44-9
• Molecular Weight: 0
• EINECS: 232-912-1
• Product Categories: 3.1.x.x Acting on esters;3.x.x.x Hydrolases;Enzyme Class Index
• Mol File: 9037-44-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /buffered aqueous glycerol solution
• Storage Temp.: −20°C
• CAS DataBase Reference: EXONUCLEASE III(CAS DataBase Reference)
• NIST Chemistry Reference: EXONUCLEASE III(9037-44-9)
• EPA Substance Registry System: EXONUCLEASE III(9037-44-9)

Safety Data

• Safety Statements: 36
• WGK Germany: 3
• Hazardous Substances Data: 9037-44-9(Hazardous Substances Data)

Usage

General Description

Exonuclease III is a type of enzyme that plays a crucial role in DNA repair and recombination processes in cells. It belongs to the exonuclease family, which is responsible for removing nucleotides from the ends of DNA molecules. Specifically, Exonuclease III possesses 3' to 5' exonuclease activity, allowing it to cleave phosphodiester bonds and remove mono-, di-, or trinucleotides from the 3' end of double-stranded DNA. This enzyme is involved in the repair of DNA damage caused by a variety of factors, such as radiation, oxidative stress, and certain chemicals, and is essential for maintaining genomic stability and integrity. Additionally, Exonuclease III has been widely used in biotechnology and molecular biology research as a tool for DNA manipulation and sequencing.