90377-06-3Relevant academic research and scientific papers
Synthesis of coumarins by ring-closing metathesis using Grubbs' catalyst
Nguyen Van, Tuyen,Debenedetti, Silvia,De Kimpe, Norbert
, p. 4199 - 4201 (2007/10/03)
A novel generally applicable synthesis of coumarins from phenolic substrates utilizing ring-closing metathesis is described. This sequence involves O-allylation of phenols followed by ortho-Claisen rearrangement, subsequent based-induced isomerization affording 2-(1-propenyl)phenols, acylation with acryloyl chloride, and finally ring-closing metathesis (RCM) with Grubbs' second generation catalyst.
Biomimetic synthesis of the neolignans kadsurenone, denudatin B, O- methyl-liliflodione, and liliflol B
Horne, David A.,Yakushijin, Kenichi,Buechi, George
, p. 5443 - 5447 (2007/10/03)
Synthesis of (±)-kadsurenone (1), (±)-denudatin B (2), (±)-O-methyl- liliflodione (3a), and (±)-liliflol B (14) is described. The key synthetic step is a biomimetic cationic cycloaddition between E- or Z-1,2-dimethoxy-4- propenylbenzene (11) and ortho-qui
