90396-00-2 Usage
Uses
Used in Pharmaceutical Industry:
3-(4-CHLORO-BENZENESULFONYL)-PROPIONIC ACID is utilized as an active pharmaceutical ingredient for the development of medications aimed at reducing inflammation and pain. Its NSAID classification makes it suitable for the treatment of various conditions.
Used in Treatment of Arthritis:
In the medical field, particularly for rheumatology, 3-(4-CHLORO-BENZENESULFONYL)-PROPIONIC ACID is used as a therapeutic agent for managing the symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It helps in alleviating pain, reducing inflammation, and improving the quality of life for patients suffering from these conditions.
Used in Oral Medication:
3-(4-CHLORO-BENZENESULFONYL)-PROPIONIC ACID is commonly administered orally, making it a convenient option for patients. It is available in various oral dosage forms, such as tablets and capsules, facilitating ease of use and patient compliance.
However, it is important to note that 3-(4-CHLORO-BENZENESULFONYL)-PROPIONIC ACID should be used with caution due to potential side effects, which may include gastrointestinal bleeding and kidney problems. Patients and healthcare providers should weigh the benefits against the risks when considering its use for treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 90396-00-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,3,9 and 6 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 90396-00:
(7*9)+(6*0)+(5*3)+(4*9)+(3*6)+(2*0)+(1*0)=132
132 % 10 = 2
So 90396-00-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H9ClO4S/c10-7-1-3-8(4-2-7)15(13,14)6-5-9(11)12/h1-4H,5-6H2,(H,11,12)
90396-00-2Relevant academic research and scientific papers
MODERN FRIEDEL-CRAFTS CHEMISTRY. XI. CYCLIZATION OF ARYL HALOALKYL SULFONES, ARYLSULFONYLACYL CHLORIDES AND THEIR CORRESPONDING SULFIDES
Abdel-Wahab, Aboel-Magd A.,El-Khawaga, Ahmed M.,El-Zohry, Maher F.,Khalaf, Ali A.
, p. 31 - 44 (2007/10/02)
The sulfone group deactivation for cyclialkylation and cycliacylation reactions in the presence of Friedel-Crafts catalysts was demonstrated in a number of aryl chloroalkylsulfones (1-8) and arylsulfonylacyl chlorides (17a-22a), respectively.As expected, the corresponding arylchloroalkyl sulfides (9-16) and arylmercaptoacyl chlorides (13a-28a) underwent ring-closure reaction in most cases under the same conditions.The ease of cyclization was governed by the ring size, the stability of the attacking carbocation and the nucleophilicity of the aryl moiety.Also, the behaviour of benzyl sulfones (29, 31a, and 32a) and sulfides (33, 34a and 36a) was inconsistent.Noteworthy, the Friedel-Crafts cyclization reaction is thus considered an accessible method for the synthesis of compounds 37-41 and 45, 51.
