Vernamycin B, also known as virginiamycin B, is a complex polyether ionophore antibiotic produced by Streptomyces virginiae, a soil-dwelling bacterium. It is a member of the vernamycin family, which includes several closely related compounds, and is primarily used as a growth promoter and feed additive in animal husbandry to enhance feed efficiency and prevent bacterial infections. Vernamycin B works by disrupting the bacterial cell membrane, leading to the leakage of essential ions and nutrients, ultimately causing cell death. Its mechanism of action is similar to that of other ionophores, such as monensin and salinomycin, and it is particularly effective against gram-positive bacteria. Due to its potential for cross-resistance with other ionophores and concerns about antibiotic resistance, its use in human medicine is limited, but it remains an important tool in veterinary medicine.
The CAS Registry Mumber 9040-14-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,4 and 0 respectively; the second part has 2 digits, 1 and 4 respectively. Calculate Digit Verification of CAS Registry Number 9040-14: (6*9)+(5*0)+(4*4)+(3*0)+(2*1)+(1*4)=76 76 % 10 = 6 So 9040-14-6 is a valid CAS Registry Number.