Gelatinase is a type of proteolytic enzyme, primarily found in the matrix metalloproteinase (MMP) family, which plays a crucial role in the degradation and remodeling of extracellular matrix (ECM) components, such as collagen and gelatin. These enzymes are involved in various physiological processes, including tissue repair, angiogenesis, and immune response, as well as pathological conditions like cancer progression, inflammation, and tissue destruction. Gelatinases, specifically MMP-2 and MMP-9, are secreted as inactive proenzymes and require activation through proteolytic cleavage. Their activity is tightly regulated to maintain ECM homeostasis, and imbalances in gelatinase expression or function can lead to various diseases.
The CAS Registry Mumber 9040-48-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,4 and 0 respectively; the second part has 2 digits, 4 and 8 respectively. Calculate Digit Verification of CAS Registry Number 9040-48: (6*9)+(5*0)+(4*4)+(3*0)+(2*4)+(1*8)=86 86 % 10 = 6 So 9040-48-6 is a valid CAS Registry Number.