9040-59-9 Usage
Uses
Used in Calmodulin Assay:
3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE is used as an assay tool for calmodulin, a calcium-binding protein involved in various cellular processes. The activity of this enzyme is significantly reduced to less than 50% without the presence of calmodulin, making it an essential component in the assay.
Used in In Vitro Adenylate Cyclase Assay:
In the field of molecular biology and biochemistry, 3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE from bovine brain is utilized as a reagent in in vitro adenylate cyclase assays. Adenylate cyclase is an enzyme that catalyzes the conversion of ATP to cAMP, which is a key player in signal transduction pathways. The use of this enzyme in the assay helps in studying the regulation and activity of adenylate cyclase, providing valuable insights into cellular signaling mechanisms.
Biochem/physiol Actions
Hydrolyzes the 3′,5′-phosphodiester bond in cyclic nucleotide monophosphates, such as cAMP and cGMP, to the corresponding nucleotide 5′-monophosphate.
Clinical Use
Phosphodiesterase-3 (PDE3) is an enzyme responsible for degradation of cAMP to AMP in platelets
and blood vessels. Selective cAMP PDE3 inhibitors, such as dipyridamole and cilostazol , inhibit the degradation of cAMP, thereby increasing cellular concentration of cAMP and
leading to inhibition of platelet aggregation and vasodilation.
Check Digit Verification of cas no
The CAS Registry Mumber 9040-59-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,4 and 0 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 9040-59:
(6*9)+(5*0)+(4*4)+(3*0)+(2*5)+(1*9)=89
89 % 10 = 9
So 9040-59-9 is a valid CAS Registry Number.
