904003-02-7Relevant academic research and scientific papers
Alkylations and hydroxymethylations of pyrazines via green minisci-type reactions
Bohman, Bjorn,Berntsson, Benjamin,Dixon, Ruby C. M.,Stewart, Craig D.,Barrow, Russell A.
, p. 2787 - 2789 (2014/06/23)
A new general methodology utilizing Minisci-type chemistry has been developed that cleanly and efficiently prepares alkyl- and (hydroxymethyl) pyrazines. The new methods eliminate toxic catalysts and halogenated solvents, providing a greatly improved route to these natural products which are prevalent in many natural systems as bacterial volatiles, plant volatiles, and insect pheromones.
