Angiotensin I is a decapeptide hormone that plays a crucial role in the renin-angiotensin system, a key regulatory mechanism for blood pressure and fluid balance in the body. It is generated through the action of the enzyme renin on angiotensinogen, a liver-derived protein. Angiotensin I is then converted to the more potent vasoconstrictor angiotensin II by the angiotensin-converting enzyme (ACE). This conversion leads to increased blood pressure by constricting blood vessels and promoting the release of aldosterone, which in turn increases sodium and water reabsorption in the kidneys, leading to an increase in blood volume. Angiotensin I is also involved in the regulation of thirst and fluid intake, further contributing to the body's fluid balance.
9041-90-1
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Basic information
- Product Name: Angiotensin I
- Synonyms: Angiotensin1; Pepsitensin; Proangiotensin
- CAS NO:9041-90-1
- Molecular Formula: C62H89N17O14
- Molecular Weight: 1296.47556
- EINECS: N/A
- Product Categories: N/A
- Mol File: 9041-90-1.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: °Cat760mmHg
- Flash Point: °C
- Appearance: /
- Density: 1.42g/cm3
- Refractive Index: 1.664
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Angiotensin I(CAS DataBase Reference)
- NIST Chemistry Reference: Angiotensin I(9041-90-1)
- EPA Substance Registry System: Angiotensin I(9041-90-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 9041-90-1(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 9041-90-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,4 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.Calculate Digit Verification of CAS Registry Number 9041-90:
(6*9)+(5*0)+(4*4)+(3*1)+(2*9)+(1*0)=91
91 % 10 = 1
So 9041-90-1 is a valid CAS Registry Number.
InChI:InChI=1/C63H91N17O13/c1-8-35(6)52(78-61(92)53(38-18-20-41(82)21-19-38)79-59(90)51(34(4)5)77-56(87)44(16-12-22-70-63(66)67)73-55(86)43(64)28-49(83)84)60(91)76-47(27-40-30-69-32-72-40)62(93)80-23-13-17-48(80)58(89)75-46(25-37-14-10-9-11-15-37)57(88)74-45(26-39-29-68-31-71-39)54(85)50(65)42(36(7)81)24-33(2)3/h9-11,14-15,18-21,29-35,42-48,50-53,82H,8,12-13,16-17,22-28,64-65H2,1-7H3,(H,68,71)(H,69,72)(H,73,86)(H,74,88)(H,75,89)(H,76,91)(H,77,87)(H,78,92)(H,79,90)(H,83,84)(H4,66,67,70)/t35-,42-,43-,44-,45-,46-,47-,48-,50?,51-,52-,53-/m0/s1
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Angiotensin I
