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9041-93-4

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Product FOB Price Min.Order Supply Ability Supplier
Bleomycin Sulfate
Cas No: 9041-93-4
No Data No Data 5 Hangzhou J&H Chemical Co., Ltd. Contact Supplier
Bleomycin sulfate with best price and top quality
Cas No: 9041-93-4
USD $ 800.0-1000.0 / Kilogram 1 Kilogram 5000 Kilogram/Month Kono Chem Co.,Ltd Contact Supplier
Bleomycin sulfate CAS 9041-93-4
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USD $ 10.0-10.0 / Kilogram 10 Kilogram 300 Metric Ton/Year Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
Bleomycin sulfate
Cas No: 9041-93-4
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
High Quality 99% Bleomycin sulfate 9041-93-4 GMP Manufacturer
Cas No: 9041-93-4
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Factory Supply Bleomycin Sulfate
Cas No: 9041-93-4
No Data 1 1 Ality Chemical Corporation Contact Supplier
Bleomycin sulfate
Cas No: 9041-93-4
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Bleomycin sulfate Manufacturer/High quality/Best price/In stock
Cas No: 9041-93-4
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
9041-93-4?Bleomycin sulfate
Cas No: 9041-93-4
USD $ 1000.0-1000.0 / Kilogram 1 Kilogram 1 Metric Ton/Day Henan Tianfu Chemical Co., Ltd. Contact Supplier
New arrival CAS 9041-93-4 with fast shipping
Cas No: 9041-93-4
USD $ 146.0-176.0 / Gram 10 Gram 1000 Kilogram/Day Zhuozhou Wenxi import and Export Co., Ltd Contact Supplier

9041-93-4 Usage

Uses

Bleomycin is a complex of 11 glycopeptide antitumor antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components of the complex are bleomycin A2 and B2, which typically represent >90% of the total weight. Bleomycins have found clinical application in the treatment of a range of tumors. Bleomycins act by intercalation of DNA and RNA. In the presence of oxygen and metal ions, notably copper and iron, bleomycins form a pseudo-enzyme that induces DNA cleavage.

Chemical Properties

White Powder

Clinical Use

Bleomycin is used IV in the palliative treatment of squamous cell head and neck cancers, testicular and other genital carcinomas, and Hodgkin's and non-Hodgkin's lymphoma.

General Description

Bleomycin occurs as a white powder and is available in 15-and 30-U vials for reconstitution in water. It may be givenintravenously, intramuscularly, or subcutaneously. It is used in the treatment of squamous cell carcinoma of the headneck, cervix, penis, and vulva. It is also used in Hodgkin’sand non-Hodgkin’s lymphoma as well as testicular carcinoma.Unlabeled uses include the treatment of mycosis fungoides,osteosarcoma, and AIDS-related Kaposi sarcoma.

Uses

Bleomycin is a complex of 11 glycopeptide antitumour antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components of the complex are bleomycin A2 and B2, which typically represent >90% of the total weight . Bleomycins have found clinical application in the treatment of a range of tumours. Bleomycins act by intercalation of DNA and RNA. In the presence of oxygen and metal ions, notably copper and iron, bleomycins form a pseudo-enzyme that induces DNA cleavage.

Veterinary Drugs and Treatments

Bleomycin has occasionally been used as adjunctive treatment of lymphomas, squamous cell carcinomas, teratomas, and nonfunctional thyroid tumors in both dogs and cats. Recent work has demonstrated that bleomycin may be promising for intralesional treatment for a variety of localized tumors with or without concomitant electropermeabilization.

Uses

A group of related glycopeptide antibiotics. Bleomycin A2 is the main component of the bleomycin employed clinically. Antineoplastic

Side effects

It is excreted via the kidneys, and serum concentrations of active drug are increased in patients with renal disease. The elimination half-life can rise from 2 to 4 hours to more than 20 hours in renal failure, resulting in significant toxicity, especially pulmonary toxicity.

Brand name

Blenoxane (Bristol-Myers Squibb).
InChI:InChI=1/C52H77N13O19S3/c1-7-11-54-18-32-56-13-9-26(62-32)45(75)65-35(41(27-16-55-22-60-27)82-51-43(39(72)37(70)29(19-66)81-51)83-50-40(73)42(84-52(53)79)38(71)30(20-67)80-50)48(78)61-24(3)36(69)23(2)44(74)64-34(25(4)68)47(77)58-14-10-33-63-28(21-85-33)49-59-17-31(86-49)46(76)57-12-8-15-87(5)6/h9,13,16-17,21-25,29-30,34-43,50-51,54,66-73H,7-8,10-12,14-15,18-20H2,1-6H3,(H7-,53,55,57,58,60,61,64,65,74,75,76,77,78,79)/p+1/t23-,24+,25?,29+,30+,34?,35+,36-,37+,38-,39+,40-,41+,42+,43-,50-,51+/m0/s1

9041-93-4 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (B3972)  Bleomycin Sulfate (mixture)  >85.0%(HPLC) 9041-93-4 10mg 550.00CNY Detail
TCI America (B3972)  Bleomycin Sulfate (mixture)  >85.0%(HPLC) 9041-93-4 50mg 1,990.00CNY Detail

9041-93-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Bleomycin sulfate

1.2 Other means of identification

Product number -
Other names Blenmycins

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:9041-93-4 SDS

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