90421-18-4

Upstream product

• 90421-19-5 threo-2-(α-hydroxybenzyl)-N,N,3-trimethylbutanamide 
• 67797-33-5 N,N-Dimethylisovalerothioamide 
• 90421-19-5 erythro-2-(α-hydroxybenzyl)-N,N,3-trimethylbutanamide 
• 100-52-7 benzaldehyde 
• 5370-28-5 N,N-dimethylisovaleramide 
• 78175-54-9 (S)-2-((R)-Hydroxy-phenyl-methyl)-3,N,N-trimethyl-thiobutyramide 

Relevant academic research and scientific papers

SUR LES ORGANOMETALLIQUES ISSUS DE THIOAMIDES. I. REACTIVITE AVEC LES ALDEHYDES ET CETONES; STEREOCHIMIE DE LA CONDENSATION AVEC LA t-BUTYL-4 CYCLOHEXANONE ET LE BENZALDEHYDE

Organometallic compounds derived from thioamides RCH2CSN(R3)2 condense normally with aldehydes and saturated ketones.Condensation with 4-t-butylcyclohexanone leads predominantly to equatorial attack by the organometallic compound.These results suggest that the organometallic structure is RCH=C(SM)N(R3)2.The stereoselectivity of the reaction with benzaldehyde depends on R and R3; a mechanism for the formation of β-hydroxythioamides is discussed.