904328-01-4Relevant articles and documents
Reduction of bis(5-alkyl-2-furyl)(2-nitroaryl)methane with aqueous titanium trichloride solution
Deng, Wei,Li, Dong-Kun,Tan, Jing-Yi,Xu, Zheng-Yang
supporting information, (2021/09/29)
In this article, we introduces a new method for the synthesis of substituted indole by reductive recyclization of bis(5-alkyl-2-furyl)(2-nitroaryl)methane. Bis(5-alkyl-2-furyl)(2-nitroaryl)methane undergo reduction to provide indole or aniline. In the pro
Furan ring opening-indole ring closure: Synthesis of furo[2′, 3′:3,4]-cycloheota[1,2-b]indolium chlorides
Butin, Alexander V.,Smirnov, Sergey K.,Stroganova, Tatyana A.
, p. 623 - 628 (2007/10/03)
A new synthetic approach to furo[2′,3′:3,4]cyclohepta[1,2-b] indolium chlorides is elaborated starting from 2-acetylaminoaryldifurylmethanes or 2-aminoaryldifurylmethanes under treatment with methanolic HCl solution. The reaction proceeds in three steps: recyclization, intramolecular cyclization, and disproportionation. In this case the furan ring takes part in building up both pyrrole and seven-membered rings. The same salts can be obtained directly from 2-acetylaminobenzaldehydes and 2-methylfuran under similar conditions without isolation of corresponding 2-acetylaminoaryldifurylmethanes.