90433-08-2

Basic information

• Product Name: 5-(1'H-tetrazol-5'-yl)-1H-indole
• Synonyms: 5-(1'H-tetrazol-5'-yl)-1H-indole
• CAS NO: 90433-08-2
• Molecular Formula: C₉H₇N₅
• Molecular Weight: 185.18538
• Mol File: 90433-08-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(1'H-tetrazol-5'-yl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(1'H-tetrazol-5'-yl)-1H-indole(90433-08-2)
• EPA Substance Registry System: 5-(1'H-tetrazol-5'-yl)-1H-indole(90433-08-2)

Safety Data

• Hazardous Substances Data: 90433-08-2(Hazardous Substances Data)

Upstream product

• 15861-24-2 1H-indole-5-carbonitrile 

Downstream Products

• 15861-24-2 1H-indole-5-carbonitrile 
• 720697-00-7 5-(2-trityl-2H-tetrazol-5-yl)-1H-indole 
• 720695-45-4 5-(2H-tetrazol-5-yl)-1-[3-(trifluoromethyl)benzyl]-1H-indole 

Relevant articles and documents

Urea mediated 5-substituted-1H-tetrazole via [3?+?2] cycloaddition of nitriles and sodium azide

A simple, new and convenient metal free procedure for the synthesis of 5-substituted 1H-tetrazoles using various nitriles and sodium azide in the presence of urea and acetic acid with good to high yields is developed. The reaction plausibly proceeds through in situ formation of urea azide active complex without toxic and/or expensive metal catalysts.

Choline chloride–ZnCl2: Recyclable and efficient deep eutectic solvent for the [2+3] cycloaddition reaction of organic nitriles with sodium azide

Herein we report first time choline chloride–zinc chloride based deep eutectic solvent is a green and efficient reaction medium for the [2+3] cycloaddition reaction of organic nitriles with sodium azide to afford the corresponding 5-substituted 1H-tetrazo

Facile synthesis of 5-substituted 1H-tetrazoles catalyzed by tetrabutylammonium hydrogen sulfate in water

Facile synthesis of 5-substituted 1H-tetrazoles was achieved by treating nitriles with NaN3 in water or toluene in the presence of tetrabutylammoniumhydrogen sulfate (TBAHS). The reaction could be carried out in water as well as in toluene. The

An efficient synthesis of 5-substituted 1H-tetrazoles via B(C 6F5)3 catalyzed [3+2] cycloaddition of nitriles and sodium azide

A simple and efficient protocol is developed for the synthesis of 5-substituted 1H-tetrazole derivatives from various nitriles and sodium azide (NaN3) via [3+2] cycloaddition reaction using B(C6F 5)3 as a catalyst. The present synthetic method displayed significant advantages such as low catalyst loading, mild reaction conditions, low toxicity, easy work-up, high yields, and compatibility with other functional groups.

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