90448-25-2

Basic information

• Product Name: 2H-1-Benzopyran, 8-methyl-
• CAS NO: 90448-25-2
• Molecular Formula: C10H10O
• Molecular Weight: 146.189
• Mol File: 90448-25-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran, 8-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran, 8-methyl-(90448-25-2)
• EPA Substance Registry System: 2H-1-Benzopyran, 8-methyl-(90448-25-2)

Safety Data

• Hazardous Substances Data: 90448-25-2(Hazardous Substances Data)

Relevant articles and documents

Synthesis of 2 h-chromenes via hydrazine-catalyzed ring-closing carbonyl-olefin metathesis

The catalytic ring-closing carbonyl-olefin metathesis (RCCOM) of O-Allyl salicylaldehydes to form 2H-chromenes is described. The method utilizes a [2.2.1]-bicyclic hydrazine catalyst and operates via a [3 + 2]/retro-[3 + 2] metathesis manifold. The nature of the allyl substitution pattern was found to be crucial, with sterically demanding groups such as adamantylidene or diethylidene offering optimal outcomes. A survey of substrate scope is shown along with a discussion of mechanism supported by DFT calculations. Steric pressure arising from syn-pentane minimization of the diethylidene moiety is proposed to facilitate cycloreversion.