90463-22-2Relevant academic research and scientific papers
Dihydropyridine anti-ischaemic and antihypertensive agents
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, (2008/06/13)
1,4-Dihydropyridine derivatives of the formula: STR1 wherein R is aryl or heteroaryl: R1 and R2 are each independently C1 -C4 alkyl or 2-methoxyethyl; Y is --(CH2)n --, --CH2 CH(CH3)-- or --CH2 C(CH3)2 --; n is 1 to 3; and X is a 5 or 6 membered nitrogen containing aromatic heterocyclic ring which may optionally be substituted by one or more C1 -C4 alkyl, phenyl, benzyl, CN, --N(R3)2, (CH2)m CO2 H, (CH2)m CO2 (C1 -C4 alkyl) or (CH2)m CON(R3)2 group wherein each R3 is independently H or C1 -C4 alkyl and m is 0 or 1; and their pharmaceutically acceptable acid addition salts, and pharmaceutical preparation containing such compounds, have utility as anti-ischaemic and antihypertensive agents.
Dihydropyridine anti-ischaemic and antihypertensive agents
-
, (2008/06/13)
1,4-Dihydropyridine derivatives of the formula: STR1 wherein R is aryl or heteroaryl; R1 and R2 are each independently C1 -C4 alkyl or 2-methoxyethyl; Y is --(CH2)n --, --CH2 CH(CH3)-- or --CH2 C(CH3)2 13 ; n is 1 to 3; and X is a 5 or 6 membered nitrogen containing aromatic heterocyclic ring which may optionally be substituted by one or more C1 -C4 alkyl, phenyl, benzyl, CN, --N(R3)2, (CH2)m CO2 H, (CH2)m CO2 (C1 -C4 alkyl) or (CH2)m CON(R3)2 group wherein each R3 is independently H or C1 -C4 alkyl and m is 0 or 1; and their pharmaceutically acceptable acid addition salts, and pharmaceutical preparation containing such compounds, have utility as anti-ischaemic and antihypertensive agents.
Dihydropyridine anti-ischaemic and anti-hypertensive agents, compositions and use
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, (2008/06/13)
Dihydropyridine anti-ischaemic and anti-hypertensive agents of the formula: STR1 and their pharmaceutically acceptable salts; wherein R is aryl or heteroaryl; R1 and R2 are each independently C1 -C4 or 2-methoxy
