90473-80-6Relevant academic research and scientific papers
Versatile novel syntheses of imidazoles
Rolfs, Andreas,Liebscher, Juergen
, p. 3480 - 3487 (2007/10/03)
A novel ring transformation/desulfurization of substituted 2-methyl-1,2,4-thiadiazolium salts 2 provides a versatile entry to imidazoles 3 with a variety of substituents. Simple one-pot procedures combine the preparation of starting 1,2,4-thiadiazolium salts 2 from N-(thiocarbonyl)-N'-methylamidines 1 or 1,2,4-dithiazolium triiodides 6 with the ring transformation/desulfurization to the imidazoles 3. Alternatively, N-(thiocarbonyl)-N'-methylamidines 1 can be transformed to imidazoles 3 or to 1-substituted imidazoles 5 via S-methylation and elimination of methylthiol. In the same manner, a new entry to 4H-imidazoles 8 could be developed.
REAKTIONEN AN NICKEL(II)KOORDINIERTEN N-ACYLTHIOHARNSTOFFEN MIT SAEURECHLORIDEN: EIN EINFACHER ZUGANG FUER NEUE THIOHARNSTOFF-DERIVATE
Beyer, L.,Hartung, J.,Widera, R.
, p. 405 - 412 (2007/10/02)
The reaction of transition metal coordinated N,N-dialkylsubstituted N'-benzoyl thioureas with electrophilic agents differs from the reaction of the non-coordinated ligands.The nickel(II)chelates 1 form with organic acid chlorides RCOCl the N',N'-diacylate
