904744-84-9

Upstream product

• 452-63-1 2-Bromo-5-fluorotoluene 
• 202865-66-5 2-bromo-5-fluorobenzyl alcohol 
• 112399-50-5 2-bromo-5-fluorobenzyl bromide 
• 24470-78-8 isopropyltriphenylphosphonium iodide 
• 94569-84-3 2-bromo-5-fluorobenzaldehyde 

Downstream Products

• 904744-85-0 4-fluoro-2-(2-methyl-propenyl)-benzaldehyde 
• 1111310-72-5 ethyl 2-(4-fluoro-2-(2-methylpropenyl)phenyl)-2-hydroxyacetate 
• 1111311-01-3 ethyl 2-(4-fluoro-2-(2-methylpropenyl)phenyl)-2-(methylsulfonyloxy)acetate 
• 904744-86-1 1-[4-fluoro-2-(2-methyl-propenyl)-phenyl]-3-trimethylsilanyl-prop-2-yn-1-ol 
• 904744-31-6 1-(4-fluoro-2-(2-methylprop-1-enyl)phenyl)-prop-2-yn-1-ol 

Relevant academic research and scientific papers

Orthogonal synthesis of isoindole and isoquinoline derivatives from organic azides

(Chemical Equation Presented) α-Azido carbonyl compounds bearing a 2-alkenylaryl moiety at the α-position are found to be promising precursors for synthesis of isoindole and isoquinoline derivatives via 1,3-dipolar cycloaddrtion of azides onto alkenes and fcrelectrocyclization of N-H imine intermediates, respectively.

Metal-catalyzed cycloisomerization of enyne functionalities via a 1,3-alkylidene migration

We report a new metal-catalyzed 6-endo-dig cyclization of cis-4,6-dien-1-yn-3-ols, which produces substituted benzene and naphthalene derivatives with structural reorganization. In this process, we observe a 1,3-alkylidene migration via cleavage of the olefin double bond of the starting substrates. The ease and reliability of this cyclization are manifested by its compatibility with a wide array of diverse substrates and several π-alkyne activators, including PtCl2, Zn(OTf)2, AuCl, and AuCl3. Copyright