Ribonuclease H, also known as Rnase H, is an enzyme that plays a crucial role in the maturation and repair of RNA molecules. It is found in various organisms, including Escherichia coli, and has been extensively studied for its potential applications in various fields.
9050-76-4
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Basic information
- Product Name: RIBONUCLEASE H
- Synonyms: EC 3.1.4.34;RIBONUCLEASE H;RNASE H;ribonuclease H from E. coli rnase*H gene;ribonuclease h from escherichia coli;Ribonulease H;Nuclease, hybrid ribo-
- CAS NO:9050-76-4
- Molecular Formula:
- Molecular Weight: 0
- EINECS: 1806241-263-5
- Product Categories: Nucleotide MetabolismEnzymes, Inhibitors, and Substrates;Protein&Nucleic Acid IsolationEnzyme Class Index;3.1.x.x Acting on esters;3.x.x.x Hydrolases;Application Index;General Metabolic Enzymes;Metabolomics
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /buffered aqueous glycerol solution
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: RIBONUCLEASE H(CAS DataBase Reference)
- NIST Chemistry Reference: RIBONUCLEASE H(9050-76-4)
- EPA Substance Registry System: RIBONUCLEASE H(9050-76-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 1
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 9050-76-4(Hazardous Substances Data)
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9050-76-4 Usage
Uses
Used in Biochemistry Research:Ribonuclease H is used as a research tool for studying the metallobiochemistry of the magnesium ion. It helps in understanding the role of magnesium in RNA processing and stability.
Used in Pharmaceutical Industry:
Ribonuclease H is used as a target for the development of selective inhibitors of HIV-1 reverse transcriptase associated Rnase H activity. These inhibitors can potentially be used in the treatment of HIV/AIDS by blocking the replication of the virus.
Used in Molecular Biology:
Ribonuclease H is used in various molecular biology techniques, such as RNA interference (RNAi) and CRISPR-Cas gene editing, where it is employed to degrade specific RNA molecules and regulate gene expression.
Check Digit Verification of cas no
The CAS Registry Mumber 9050-76-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,5 and 0 respectively; the second part has 2 digits, 7 and 6 respectively.Calculate Digit Verification of CAS Registry Number 9050-76:
(6*9)+(5*0)+(4*5)+(3*0)+(2*7)+(1*6)=94
94 % 10 = 4
So 9050-76-4 is a valid CAS Registry Number.
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RIBONUCLEASE H
