90511-11-8Relevant academic research and scientific papers
CYCLOBUTANONES FOR THE STEREOSELECTIVE SYNTHESIS OF BIFUNCTIONAL MACROLIDE INTERMEDIATES
Frater, G.,Mueller, U.,Guenther, W.
, p. 1133 - 1136 (1984)
Beckmann fragmentation of the oximes 5 and 6 respectively, which were derived from the cyclobutanones 3 and 4, furnished the bifunctional five carbon units 7 and 8 with ca. 98percent and 91percent stereoselectivity.
Kinetic resolution in the [2+2] cycloaddition of ketenes: An experimental and theoretical study
Rullire, Pauline,Carret, Sbastien,Milet, Anne,Poisson, Jean-Franois
supporting information, p. 3876 - 3881 (2015/10/19)
The kinetic resolution of Z and E olefins by [2+2] cycloaddition with ketenes allows the isolation of pure E olefin, as well as the synthesis of pure cis-cyclobutanones, starting from Z/E mixtures. A computational rationale for this kinetic difference is reported. The obtained difference of energy of activation matches with the experimental results.
