90521-88-3Relevant academic research and scientific papers
8 - SULFO - IMIDAZOTETRAZIN- 4 - ONE COMPOUNDS AND THEIR USE AS ANTICANCER DRUG
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Page/Page column 78, (2012/07/13)
Compounds of formula (I) and pharmaceutically acceptable salts, hydrates or solvates thereof are provided (I) wherein B, X, and Y are as defined herein. The compounds are of use in methods of regulating cell proliferation, inhibiting cell cycle progressio
Antitumor Imidazotetrazines. 14. Synthesis and Antitumor Activity of 6- and 8-Ssubstituted Imidazo-1,2,3,5-tetrazinones and 8-Substituted Pyrazolo-1,2,3,5-tetrazinones
Lunt, Edward,Newton, Christopher G.,Smith, Christopher,Stevens, Graham P.,Stevens, Malcolm F. G.,et al.
, p. 357 - 366 (2007/10/02)
The systematic variation of the potent antitumor agent mitozolomide (1) is extended to cover alteration of substituents at position 6 and 8 and to change the imidazo-1,2,3,5-tetrazinone (6) skeleton to the isomeric pyrazolo-1,2,3,5-tetrazino
