905261-90-7Relevant academic research and scientific papers
Synthesis and anti tuberculostatic activity of novel 1,3,4-oxadiazole derivatives
Shahar Yar,Ahmad Siddiqui,Ashraf Ali
, p. 5 - 8 (2008/02/13)
A series of novel 2,5-disubstituted 1,3,4-oxadiazole derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed interesting activity against a strain of Mycobacterium tuberculosis H37Rv. The result of the antimycobacterial activity tests revealed that 2-(2-naphthyloxymethyl)-5-phenoxymethyl-1,3,4-oxadiazole (IVd) exhibited > 90% inhibition at MIC ~6.25.
