905273-66-7 Usage
Uses
Used in Pharmaceutical Industry:
3-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine is used as a building block for the synthesis of biologically active compounds due to its distinctive structure and chemical properties. Its incorporation into new drug development may lead to the creation of innovative pharmaceuticals with improved therapeutic effects.
Further research and development are necessary to explore the full potential of 3-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine and uncover additional applications in various industrial and scientific fields. The unique characteristics of 3-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine may pave the way for new discoveries and advancements in multiple domains.
Check Digit Verification of cas no
The CAS Registry Mumber 905273-66-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,5,2,7 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 905273-66:
(8*9)+(7*0)+(6*5)+(5*2)+(4*7)+(3*3)+(2*6)+(1*6)=167
167 % 10 = 7
So 905273-66-7 is a valid CAS Registry Number.
905273-66-7Relevant academic research and scientific papers
Discovery of benzoylisoindolines as a novel class of potent, selective and orally active GlyT1 inhibitors
Pinard, Emmanuel,Alberati, Daniela,Bender, Markus,Borroni, Edilio,Brom, Virginie,Burner, Serge,Fischer, Holger,Hainzl, Dominik,Halm, Remy,Hauser, Nicole,Jolidon, Synse,Lengyel, Judith,Marty, Hans-Peter,Meyer, Thierry,Moreau, Jean-Luc,Mory, Roland,Narquizian, Robert,Norcross, Roger D.,Schmid, Philipp,Wermuth, Roger,Zimmerli, Daniel
scheme or table, p. 6960 - 6965 (2011/02/16)
Benzoylisoindolines were discovered as a novel structural class of GlyT1 inhibitors. SAR studies and subsequent lead optimization efforts focused primarily on addressing hERG liability and on improving in vivo efficacy resulted in the identification of potent GlyT1 inhibitors displaying excellent selectivity and in vivo PD and PK profiles.
