90528-94-2

Upstream product

• 308358-04-5 (6R)-2,2,6-trimethyl-1-oxaspiro[2.5]octan-4-one 
• 106-95-6 allyl bromide 
• 89-82-7 pulegone 
• 123-73-9 trans-Crotonaldehyde 
• 87894-21-1 tert-butyl 3-oxohept-6-enoate 
• 90461-82-8 Sodium; (R)-5-methyl-2-phenylsulfanyl-cyclohex-1-enolate 
• 90461-80-6 (R)-2-Allyl-5-methyl-2-phenylsulfanyl-cyclohexanone 

Downstream Products

• 20316-18-1 (-)-lycodine 
• 1438285-31-4 (R)-2-(3-azidopropyl)-5-methylcyclohex-2-enone 
• 1229041-63-7 (7aS)-3a-(3-(tert-butyldiphenylsilyloxy)propyl)-6-methyl-3-methylenetetrahydro-1H-indene-2,4(5H,6H)-dione 
• 18331-31-2 (-)-8-deoxyserratinine 
• 1207722-96-0 C₁₈H₃₂O₃Si 
• 251650-88-1 (3R,5R)-2-Allyl-2-iodo-5-methyl-3-(4-trimethylsilanyl-but-3-ynyl)-cyclohexanone 
• 251650-83-6 (3R,5R)-2-Allyl-5-methyl-3-(4-trimethylsilanyl-but-3-ynyl)-1-trimethylsilanyloxy-cyclohexene 

Relevant academic research and scientific papers

Total Synthesis of (-)-Carinatine A and (+)-Lycopladine A

An efficient synthesis of two Lycopodium alkaloids, (-)-carinatine A and (+)-lycopladine A, is achieved in eight steps. The synthesis features an intramolecular aldol reaction for assembling the 6,5-fused ring system, a subsequent Tsuji-Trost allylation for generating a quarternary carbon center, and a 6π-electrocyclization to form the pyridine ring.

Total synthesis of (+)-fawcettimine

An effective combination: With the first asymmetric total synthesis of fawcettimine (1) it has been shown that the use of organocatalytic annulation and gold(I)-catalyzed cyclization reactions provides an effective combination for the synthesis of complex molecules. The absolute configuration of 1 was established through an X-ray structure analysis of its hydrobromide. (Figure Presented).