90535-47-0Relevant academic research and scientific papers
Coupling of Trifluoroacetaldehyde N-Triftosylhydrazone with Organoboronic Acids for the Synthesis of gem-Difluoroalkenes
Ma, Yu,Reddy, Bhoomireddy Rajendra Prasad,Bi, Xihe
, p. 9860 - 9863 (2019/12/24)
The synthesis of alkyl gem-difluoroalkenes remains a difficult task in organic synthesis. Here, we report a general and efficient approach for tackling this problem by gem-difluoroolefination of trifluoroacetaldehyde N-triftosylhydrazone with organoboronic acids. This protocol is operationally simple, free of transition metals, and suitable for a broad range of organoboronic acids. Moreover, the utility of the products was demonstrated by further conversion of the gem-difluorovinyl group.
Copper-catalyzed trifluoromethylthiolation of primary and secondary alkylboronic acids
Shao, Xinxin,Liu, Tianfei,Lu, Long,Shen, Qilong
supporting information, p. 4738 - 4741 (2015/04/27)
A Cu-catalyzed trifluoromethylthiolation of primary and secondary alkylboronic acids with an electrophilic trifluoromethylthiolating reagent is described. Tolerance for a variety of functional groups was observed.
Copper-promoted trifluoromethylation of primary and secondary alkylboronic acids
Xu, Jun,Xiao, Bin,Xie, Chuan-Qi,Luo, Dong-Fen,Liu, Lei,Fu, Yao
supporting information, p. 12551 - 12554 (2013/02/22)
New couple: The Cu-promoted trifluoromethylation of primary and secondary alkylboronic acids with TMSCF3 extends the scope of transition-metal-catalyzed trifluoromethylation reactions to sp 3-hybridized carbon centers. It also repres
