905449-88-9 Usage
Uses
N2'',?N2''''''-?[Dithiobis(1-?oxo-?3,?1-?propanediyl)?]?bis[N2''-?deacetyl- maytansine is a derivative of Mertansine (M257800) which is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Check Digit Verification of cas no
The CAS Registry Mumber 905449-88-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,5,4,4 and 9 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 905449-88:
(8*9)+(7*0)+(6*5)+(5*4)+(4*4)+(3*9)+(2*8)+(1*8)=189
189 % 10 = 9
So 905449-88-9 is a valid CAS Registry Number.
905449-88-9Relevant articles and documents
Preparation method of maytansine DM1 polymer
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Paragraph 0024-0055, (2021/05/26)
The invention discloses a preparation method of a maytansine DM1 polymer. The invention provides a preparation method of a compound as shown in a formula I. The preparation method comprises the following steps: DM1 is subjected to oxidation reaction as shown in the specification in a solvent to obtain the compound as shown in the formula I. The solvent is an amide solvent or a mixed solvent of the amide solvent and water. The preparation method of the compound I is simple in process, easy to operate, high in yield and low in cost.