905598-80-3

Upstream product

• 90632-20-5 1-[6-hydroxy-2,4-bis(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl]ethanone 
• 13709-06-3 2,4-bis(methoxymethoxy)benzaldehyde 
• 1351279-84-9 3-(2,4-bis(methoxymethoxy)phenyl)-1-(6-hydroxy-2,4-bis(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl)prop-2-en-1-one 

Relevant academic research and scientific papers

Pharmacophore identification, virtual screening and biological evaluation of prenylated flavonoids derivatives as PKB/Akt1 inhibitors

A total of 24 well-defined PKB/Akt1 inhibitors were used to generate pharmacophore models applying Catalyst/HypoGen program. The best ranked model (Hypo-1) was then validated by cost analysis, prediction capability, Cat-Scramble and receiver operating cha