90560-22-8Relevant academic research and scientific papers
AMINOGUANIDINE HYDRAZONES AS RETROMER STABILIZERS USEFUL FOR TREATING NEUROLOGICAL DISEASES
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Page/Page column 21; 46; 50-52, (2020/10/20)
The present invention relates to novel aminoguanidine hydrazone-derivatives of Formula (I) which are effective as retromer stabilizers and useful as neuroprotecting drugs. The invention also relates to pharmaceutical compositions comprising the compounds and their use in therapy and diagnostic.
Synthesis, anionophoric activity and apoptosis-inducing bioactivity of benzimidazolyl-based transmembrane anion transporters
Yu, Xi-Hui,Peng, Chen-Chen,Sun, Xiao-Xiao,Chen, Wen-Hua
supporting information, p. 115 - 125 (2018/05/03)
In this paper we show that a series of 1,3-bis(benzimidazol-2-yl)benzene (m-Bimbe) derivatives exhibit excellent performance as transmembrane anion transporters with anticancer activity. The transport efficiency of m-Bimbe and its derivatives has been fir
Externally and Internally Functionalized Copper(II) β-Diketonate Molecular Squares
Cherutoi, Jackson K.,Sandifer, Jace D.,Pokharel, Uttam R.,Fronczek, Frank R.,Pakhomova, Svetlana,Maverick, Andrew W.
, p. 7791 - 7802 (2015/08/25)
Five functionalized bis(β-diketones) and their Cu(II) molecular squares are described. The new bis(β-diketones), m-pbhxH2 (3), 5-MeO-m-pbaH2 (4), 5-BuO-m-pbaH2 (5), 2-MeO-m-pbaH2 (6), and 2-MeO-m-pbprH2/su
Versatile syntheses of optically pure pce pincer ligands: Facile modifications of the pendant arms and ligand backbones
Yang, Xiang-Yuan,Tay, Wee Shan,Li, Yongxin,Pullarkat, Sumod A.,Leung, Pak-Hing
supporting information, p. 1582 - 1588 (2015/05/13)
A series of chiral C-stereogenic PCP and PCN ligand precursors were prepared in situ from inexpensive achiral starting materials via a simple catalytic asymmetric P-H addition reaction in good overall yields. This facile catalytic method of preparing the ligand backbones renders easy and economical modifications of the electronically crucial para-substituent, chiral functionalities, and donor atoms for different transition metal ions. A one-pot synthetic procedure was used efficiently to prepare the corresponding optically pure pincer complexes. All the new complexes were characterized by NMR and mass spectroscopy. The molecular structures of several selected complexes have also been elucidated by X-ray crystallography. Preliminary studies indicated that minor structural changes on these novel pincer complexes affect their chemical properties significantly when they were applied as catalysts for the reaction between diphenylphosphine and chalcone.
Double Wittig reactions with 4-carboxybutylidene triphenylphosphorane as the key step in the synthesis of benzene derivatives metadisubstituted with ωω'-difunctionalized six-carbon chains
Provent, Christophe,Chautemps, Pierre,Gellon, Gisele,Pierre, Jean-Louis
, p. 1393 - 1396 (2007/10/03)
Using a double Wittig reaction from diformylbenzene derivatives, a direct synthetic way to 1,3-di(5-carboxypent-1-yl)benzene compounds is discussed.
