90568-96-0Relevant academic research and scientific papers
Decarboxylative Transamination. A New Route to Spirocyclic and Bridgehead-nitrogen Compounds. Relevance to α-Amino Acid Decarboxylases
Grigg, Ronald,Aly, Moustafa F.,Sridharan, Visuvanathar,Thianpatanagul, Sunit
, p. 182 - 183 (2007/10/02)
N-Substituted and α,α-disubstituted amino acids react with carbonyl compounds to generate 1,3-dipolar species under mild conditions mimicking α-amino acid decarboxylases; the 1,3-dipoles can be trapped both inter- and intra-molecularly to give bridgehead-nitrogen and spirocyclic products in good yield; pyridoxal is shown to react in an analogous fashion.
NEW PROTOTROPIC PROCESSES IN THE SYNTHESIS OF HETEROCYCLIC COMPOUNDS
Grigg, R.
, p. 593 - 604 (2007/10/02)
X=Y-ZH systems are considered in general terms and divided into four classes according to the number of constituent atoms that possess lone pair electrons.Those systems in which the central Y atom possesses a lone pair are shown to be capable of participa
