905703-53-9Relevant academic research and scientific papers
Parasite glycoconjugates. Part 16: Synthesis of a disaccharide and phosphorylated di- and tri-saccharides from Leishmania lipophosphoglycan
Ross, Andrew J.,Sizova, Olga V.,Nikolaev, Andrei V.
, p. 1954 - 1964 (2007/10/03)
A neutral disaccharide β-d-Galp-(1→4)-α-d-Manp and phosphorylated di- and tri-saccharides β-d-Galp-(1→3)-[H2PO3-6]-β-d-Galp-O[CH2]8CH{double bond, long}CH2 and β-d-Galp-(1→3)-[H2PO3-6]-β-d-Galp-(1→4)-α-d-Manp, which are fragments of the phosphoglycan portion of the surface lipophosphoglycan from Leishmania donovani (the disaccharide) or Leishmania major (all three compounds), were prepared and used as TLC standards to help the identification and differentiation of the elongating and branching β-d-galactosyl transferase activities in Leishmania. The phosphosaccharides were synthesised using the H-phosphonate method for phosphorylation.
