905754-05-4Relevant academic research and scientific papers
Pyrazolo[4,3-e][1,2,4]triazines: Purine analogues with electronic absorption in the visible region
Mojzych, Mariusz,Rykowski, Andrzej,Wierzchowski, Jacek
, p. 1298 - 1306 (2005)
Synthesis of several pryrazolo[4,3-e][1,2,4]-triazines is described. The absorption spectrum of some 5-substituted derivatives was found to extend to the visible region. These compounds were found to inhibit some enzymes of purine metabolism, like xanthine oxidase or bacterial purine-nucleoside phosphorylase with K1 values in the 10-3 10-5 M range.
