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CHEMBRDG-BB 4024586 is a synthetic derivative of the natural compound etoposide, characterized by the molecular formula C33H29NO13. It functions as a topoisomerase II inhibitor, which means it disrupts the enzyme's activity, causing DNA breaks and leading to cell death. This chemical compound has demonstrated potential as an anti-cancer agent in preclinical studies and is under further investigation for its clinical application prospects.

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  • 905811-01-0 Structure
  • Basic information

    1. Product Name: CHEMBRDG-BB 4024586
    2. Synonyms: CHEMBRDG-BB 4024586;2-bromo-N-cyclopentylbutanamide;Albb-007108;2-bromo-N-cyclopentylbutanamide(SALTDATA: FREE);2-bromo-N-cyclopentyl-butyramide;STK256817
    3. CAS NO:905811-01-0
    4. Molecular Formula: C9H16BrNO
    5. Molecular Weight: 234.14
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 905811-01-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 341.214°C at 760 mmHg
    3. Flash Point: 160.161°C
    4. Appearance: /
    5. Density: 1.313g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.507
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: CHEMBRDG-BB 4024586(CAS DataBase Reference)
    11. NIST Chemistry Reference: CHEMBRDG-BB 4024586(905811-01-0)
    12. EPA Substance Registry System: CHEMBRDG-BB 4024586(905811-01-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 905811-01-0(Hazardous Substances Data)

905811-01-0 Usage

Uses

Used in Pharmaceutical Industry:
CHEMBRDG-BB 4024586 is used as a chemotherapeutic agent for the treatment of various types of cancer. Its mechanism of action involves inhibiting topoisomerase II, which results in the accumulation of DNA breaks and ultimately induces cell death in cancerous cells.
Used in Cancer Research:
In the field of cancer research, CHEMBRDG-BB 4024586 is utilized for studying the effects of topoisomerase II inhibition on cancer cells. This research helps in understanding the compound's potential as a therapeutic agent and contributes to the development of novel cancer treatments.
Used in Drug Development:
CHEMBRDG-BB 4024586 is employed in drug development processes to create new formulations or combinations with other agents to enhance its anti-cancer properties. This may involve exploring synergistic effects with other chemotherapeutic drugs or the development of drug delivery systems to improve its efficacy and bioavailability.
Used in Preclinical Studies:
CHEMBRDG-BB 4024586 is used in preclinical studies to evaluate its safety, efficacy, and potential side effects before it can be considered for clinical trials. These studies are crucial for determining the compound's suitability for further development and eventual use in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 905811-01-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,5,8,1 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 905811-01:
(8*9)+(7*0)+(6*5)+(5*8)+(4*1)+(3*1)+(2*0)+(1*1)=150
150 % 10 = 0
So 905811-01-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H16BrNO/c1-2-8(10)9(12)11-7-5-3-4-6-7/h7-8H,2-6H2,1H3,(H,11,12)

905811-01-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-N-cyclopentylbutanamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:905811-01-0 SDS

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