905815-91-0Relevant academic research and scientific papers
The synthesis and SAR of 2-arylsulfanylphenyl-1-oxyalkylamino acids as GlyT-1 inhibitors
Smith, Garrick,Mikkelsen, Gitte,Eskildsen, Jorgen,Bundgaard, Christoffer
, p. 3981 - 3984 (2007/10/03)
Elevation of glycine levels by inhibition of the glycine transporter-1 (GlyT-1) and activation of the NMDA receptor is a potential strategy for the treatment of schizophrenia. A novel series of 2-arylsulfanylphenyl-1-oxyalkyl amino acids have been identif
AROMATIC OXYPHENYL AND AROMATIC SYLFANYLPHENYL DERIVATIVES
-
Page 45, (2008/06/13)
The present invention relates to compounds of formula I wherein the substituents are as defined below. The compounds of formula I are useful for the treatment of diseases such as schizophrenia, including both the positive and the negative symptoms of schizophrenia and other psychoses.
