905835-75-8Relevant articles and documents
Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARα and PPARγ agonist activity
Pinelli, Alessandra,Godio, Cristina,Laghezza, Antonio,Mitro, Nico,Fracchiolla, Giuseppe,Tortorella, Vincenzo,Lavecchia, Antonio,Novellino, Ettore,Fruchart, Jean-Charles,Staels, Bart,Crestani, Maurizio,Loiodice, Fulvio
, p. 5509 - 5519 (2005)
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that govern lipid and glucose homeostasis playing a central role in cardiovascular diseases, obesity, and diabetes. Medications targeted to PPARs have been esta