905858-49-3Relevant academic research and scientific papers
Solid-phase synthesis and pharmacological evaluation of a library of peptidomimetics as potential farnesyltransferase inhibitors: an approach to new lead compounds
Gilleron,Millet,Houssin,Wlodarczyk,Farce,Lemoine,Goossens,Chavatte,Pommery,Henichart
, p. 745 - 755 (2006)
Oncogenic Ras proteins whose activation is farnesylation by farnesyltransferase have been seen as important targets for novel anticancer drugs. Inhibitors of this enzyme have already been developed as potential anti-cancer drugs, particularly by rational
