905920-52-7Relevant academic research and scientific papers
Palladium-catalyzed direct N-arylation of nucleosides, nucleotides, and oligonucleotides for efficient preparation of dG-N2 adducts with carcinogenic amino-/nitroarenes
Takamura-Enya, Takeji,Enomoto, Shigeki,Wakabayashi, Keiji
, p. 5599 - 5606 (2007/10/03)
A method for direct palladium-catalyzed N-arylation reaction of nucleobases was developed for the convenient synthesis of DNA adducts with carcinogenic compounds. Using xantphos as the phosphine ligand and tetraethylammonium fluoride as the base in DMSO,
