905946-69-2Relevant academic research and scientific papers
Highly chiral muscarinic ligands: The discovery of (2S,2′R,3′S, 5′R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist
Scapecchi, Serena,Matucci, Rosanna,Bellucci, Cristina,Buccioni, Michela,Dei, Silvia,Guandalini, Luca,Martelli, Cecilia,Manetti, Dina,Martini, Elisabetta,Marucci, Gabriella,Nesi, Marta,Romanelli, Maria Novella,Teodori, Elisabetta,Gualtieri, Fulvio
, p. 1925 - 1931 (2006)
By further steric complication of previously studied highly chiral muscarinic agonists, we have obtained a small chiral library of enantiomeric and diasteromeric 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxides. Binding studies on cloned
