905982-94-7Relevant academic research and scientific papers
A [3+3] annelation approach to tetrahydropyridines
Pattenden, Lisa C.,Wybrow, Robert A. J.,Smith, Stephen A.,Harrity, Joseph P. A.
, p. 3089 - 3091 (2006)
A stepwise [3+3] annelation sequence to tetrahydropyridines via addition of the Buchi Grignard to aziridines has been developed. These intermediates can be further functionalized with good regio- and stereocontrol and this methodology has been employed in
Development of a [3+3] approach to tetrahydropyridines and its application in indolizidine alkaloid synthesis
Pattenden, Lisa C.,Adams, Harry,Smith, Stephen A.,Harrity, Joseph P.A.
, p. 2951 - 2961 (2008/09/19)
A stepwise [3+3] annelation sequence is described that generates tetrahydropyridines from the corresponding aziridines. The scope of this process is described and its potential for the stereoselective synthesis of indolizidines is highlighted by the synth
