905984-30-7Relevant academic research and scientific papers
Onium salt supported peptide synthesis
Roche, Céline,Pucheault, Mathieu,Vaultier, Michel,Commeron, Alain
experimental part, p. 8325 - 8334 (2010/11/03)
Task specific ionic liquids and onium salts have been used as soluble supports for peptide synthesis. These new supports combine easy monitoring, high loading capacities, large scale preparation, and homogeneous kinetics characteristics while keeping adva
Use of Functionalized Onium Salts for Peptide Synthesis
-
, (2010/12/18)
A subject of the invention is the use of a salt with a dedicated task of formula (I): [in-line-formulae]A+-L-R—OY, X?[/in-line-formulae] as soluble support for peptide synthesis, in which: X? represents a functional or non-functional anion,Y represents either a hydrogen atom, or a —COOR1 group, R1 representing in particular an alkyl group comprising 1 to 20 carbon atoms,A+ represents a cationic entity,L represents an arm, in particular an alkyl group of 3 to 20 carbon atoms,R represents in particular a group of formula —C(Ra)(Rb)—, Ra and Rb representing independently of one another in particular a hydrogen or an alkyl group, comprising 1 to 20 carbon atoms.
