90609-46-4

Usage

Substituents

Iodine, methyl, and methoxy groups

The benzene ring in this compound has three substituents

an iodine atom, two methyl groups, and one methoxy group. These groups are attached to the ring and influence the compound's chemical properties.
5. Potential uses in pharmaceuticals and organic compounds
Due to its unique chemical properties, 1-IODO-2,5-DIMETHYL-4-METHOXYBENZENE may have potential applications in the development of pharmaceuticals and other organic compounds.
6. Reactivity and potential health hazards
It is important to handle 1-IODO-2,5-DIMETHYL-4-METHOXYBENZENE with caution, as it may be reactive and pose potential health hazards to those who come into contact with it.

Upstream product

• 1706-11-2 2,5-Dimethyl-anisol 

Relevant academic research and scientific papers

Iodination of Methylated Anisoles: Unusual Aryl Methyl Replacement and Oxidations

The treatment of methylated anisoles with iodine, periodic acid, sulfuric acid, and aqueous acetic acid has resulted in iododemethylations and/or aryl methyl oxidations in addition to the expected mono- and diiodinations of the aromatic ring.Four dimethylanisoles and o-methylanisole were treated under identical conditions.Iododemethylations were observed in three of the four dimethylanisoles and aryl methyl oxidations to benzaldehydes occured with o-methylanisole and two of the dimethylanisoles.No precedence could be found for either of these reactions under the experimental conditions employed.Several possible mechanisms are discussed for these transformations.Some experimental evidence suggests that methyl oxidation to a benzaldehyde could be a prerequisite for an iododemethylation via an iodonium ion-assisted reverse Gatterman-Koch reaction; single-electron-transfer or classical electrophilic mechanisms are also consistent with the iododemethylations.

Iodination of Aromatic Ethers by Use of Benzyltrimethylammonium Dichloroiodate and Zinc Chloride

The reaction of aromatic ethers with benzyltrimethylammonium dichloroiodate(1-) in acetic acid in the presence of zinc chloride at room temperature gave iodo-substituted aromatic ethers in good yields.